摘要: 针对离散的基因芯片表达数据难以进行系统分析的问题,提出基因芯片数据的y~n曲线模型,将基因芯片数据转化为唯一的一列信号,从而可以对其进行多尺度分析。对人类胎儿脑发育过程中大脑皮质基因表达基于y~n曲线模型进行小波多尺度降噪,结果证明,y~n曲线的降噪效果比用基因芯片原始数据更好。
关键词:
基因芯片,
y~n曲线,
多尺度分析
Abstract: The model of y~n curve is set up to solve the problem that discrete gene chip data are difficult to be systematically analyzed, which makes the data be changed into a row of sole signal, and can be studied by multi-scale analysis. Results of denoising the cerebral cortex gene expression of developing human brain based on wavelet multi-scale analysis show that the denoised effect of y~n curve is better than that of raw data.
Key words:
DNA microarray,
y~n curve,
multi-scale analysis
中图分类号:
罗万春, 易东, 李辉智, 龚利红. 基因芯片数据多尺度分析的y~n曲线模型[J]. 计算机工程, 2011, 37(2): 20-21.
LUO Mo-Chun, YI Dong, LI Hui-Zhi, GONG Li-Gong. y~n Curve Model of Multi-scale Analysis to DNA Microarray Data[J]. Computer Engineering, 2011, 37(2): 20-21.