计算机工程

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基于MRI的开颅手术仿真系统设计

范政昂1,赵饮虹2,刘济全1,龚向阳3,孙德宇1,王 彬1,段会龙   

  1. (1. 浙江大学生物医学工程与仪器科学学院,杭州 310027;2. 中国生物技术发展中心,北京 100039; 3. 浙江大学医学院附属邵逸夫医院,杭州 310016)
  • 收稿日期:2013-04-18 出版日期:2014-07-15 发布日期:2014-07-14
  • 作者简介:范政昂(1988-),男,硕士研究生,主研方向:医学图像处理,医学可视化;赵饮虹,博士;刘济全(通讯作者),副教授;龚向阳,主任医师;孙德宇、王 彬,博士研究生;段会龙,教授。
  • 基金项目:

    国家科技支撑计划基金资助项目(2011BAI12B01);中央高校基本科研业务费专项基金资助项目(2013QNA5018)。

Design of Craniofacial Surgery Simulation System Based on MRI

FAN Zheng-ang1, ZHAO Yin-hong2, LIU Ji-quan1, GONG Xiang-yang3,SUN De-yu1, WANG Bin1, DUAN Hui-long   

  1. (1. College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, 2. China National Center for Biotechnology Development, Beijing 100039,3. Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China)
  • Received:2013-04-18 Online:2014-07-15 Published:2014-07-14

摘要:

目前临床的医学可视化工具不能准确模拟开颅手术过程,也难以获得颅脑开窗后的仿真影像来评估手术方案对颅内组织的影响。为此,设计一种面向外科手术医生的开颅手术仿真系统。相对于传统医学可视化工具针对医学影像数据进行一次性建模的方式,该系统在三维数据重建前完成关键组织区域的提取和划分,以提升分割效果的区分度,同时采用松耦合结构方便后续功能扩展。系统基于病人术前的MRI数据,自动化地提取出关键组织区域并混合绘制为多解剖结构的手术模型。手术模型可模拟开窗区域规划、手术入路、虚拟切割等开颅手术过程,并对不同解剖结构的面绘制及体绘制模型分别应用切割隐函数,以生成开窗后大脑皮层及浅表静脉等关键区域影像。实现结果表明,该系统允许医生尝试不同的手术方案,能仿真关键问题并评估方案优劣,达到减少手术风险、熟练手术步骤、提高手术精确度的目的。

关键词: 开颅手术, 手术仿真, DICOM标准, 区域分割, 医学可视化, 虚拟切割

Abstract:

Traditional clinical medical visualization tools can neither simulate the practical problems during surgical procedure, nor obtain the view after surgery to evaluate the impact on the crucial organization. The craniotomy simulation system is proposed in this paper to solve this problem. Comparing with traditional medical visualization tools, it analyses and segments the crucial tissues prior to reconstruction, and makes the rendered scene more real. In particular, it is designed as loose coupling, which benefits the following functional development in the future. Based on MRI data, it segments the crucial organization region automatically and sets up a mixture surgery model of multiple anatomical structures, which supports window regional planning, surgical approach, and the virtual cutting process. It applies cutting implicit function to multiple anatomical structure models, to provide critical areas’ scene of the cerebral cortex and superficial veins. Implementation results show that it allows doctors to validate different surgical options and evaluate the pros and cons. It has great significance on reducing the risk of surgery, training surgery procedure and improving the surgical accuracy.

Key words: craniofacial surgery, surgery simulation, DICOM criterion, region segmentation, medical visualization, virtual cutting

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