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计算机工程

• 图形图像处理 • 上一篇    下一篇

基于C-V模型和MRF的脑部MRI分割

曹沛彩1,刘晨彬1,张海石3,黄峰平3,夏顺仁1,2   

  1. (1. 浙江大学生物医学工程教育部重点实验室,杭州 310027; 2. 浙江省心脑血管检测技术与药效评价重点实验室,杭州 310027;3. 复旦大学附属华山医院,上海 200040)
  • 收稿日期:2013-01-01 出版日期:2014-03-15 发布日期:2014-03-13
  • 作者简介:曹沛彩(1989-),女,硕士研究生,主研方向:图像处理;刘晨彬,博士研究生;张海石(通讯作者),主治医师;黄峰平、夏顺仁,教授。
  • 基金资助:
    国家自然科学基金资助项目(81101903, 60772092)。

Brain MRI Segmentation Based on C-V Model and MRF

CAO Pei-cai 1, LIU Chen-bin 1, ZHANG Hai-shi 3, HUANG Feng-ping 3, XIA Shun-ren 1,2   

  1. (1. Key Lab of Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310027, China; 2. Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Hangzhou 310027, China; 3. Huashan Hospital Affiliated, Fudan University, Shanghai 200040, China)
  • Received:2013-01-01 Online:2014-03-15 Published:2014-03-13

摘要: 为准确分割脑部磁共振图像(MRI)的灰质、白质和背景,提出一种基于C-V模型和马尔可夫随机场的全自动分割方法。采用C-V模型与形态学相结合的方法对脑MRI进行预处理,去除多余脑组织,获得待分割图像。引入灰度场局部熵的思想对惩罚因子进行估计,利用马尔可夫随机场模型建模实现脑灰白质的分割,并运用形态学方法获得最终分割结果。对96幅IBSR图像和 46幅临床图像进行实验,结果表明,该方法能够实现脑部MRI灰白质的全自动分割,且具有较好的分割精度和较快的处理速度。

关键词: C-V模型, 马尔可夫随机场, 灰度场局部熵, 形态学, 脑组织分割

Abstract: In order to get gray matter, white matter and background from brain Magnetic Resonance Image(MRI) accurately, an automatic segmentation method based on C-V model and Markov Random Field(MRF) is proposed. It uses C-V algorithm and morphology to preprocess the original image and remove the unnecessary brain tissue, and the image to be segmented is got. It introduces the local entropy of the gray scale field to estimate penalty factor and Markov random field model is used to achieve the segmentation of gray matter and white matter. The segmentation result is obtained by morphological methods. Experiments are carried out on 96 pieces of IBSR images and 46 pieces of clinical images using this method, results show that the proposed method can achieve the automatic segmentation of the brain MRI and has higher accuracy as well as faster processing speed than before.

Key words: C-V model, Markov Random Field(MRF), local entropy of gray scale field, morphology, brain tissue segmentation

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