Abstract: Computer modeling is an essential method in the process of metabolic network research. Aiming at disadvantages of current tools in analysis methods and model descriptions, this paper developes a visual metabolic modeling tool based on Cytoscape plug-in. One kind of general language is defined which can describe FBA and 13C-MFA metabolic models. Functions for metabolic network modeling under graphical user interface are implemented. The result of applications shows indicates that problems in current situation can be resolved well.

Key words: metabolic network, visual modeling, Cytoscape plug-in

摘要： 针对现有代谢网络建模工具在分析方法和模型描述方面的不足，基于Cytoscape插件开发一种可视化代谢网络建模工具，定义通用的支持FBA和13C-MFA模型的代谢网络描述语言，实现图形用户界面下的代谢网络建模功能。应用结果表明，该工具能较好解决现有建模软件面临的问题。

关键词: 代谢网络, 可视化建模, Cytoscape插件

CLC Number: 

• N945.12