Abstract: To effectively integrate various distributed and heterogeneous bioinformatics resources in the Web, the bioinformatics Problem Solving Environment(PSE)——PSE-Bio based on Web Service uses the uniform client generator to add bioinformatics services provided in Web Services Description Language(WSDL) format. A PSE-Agent is used for resource management and task scheduling; Java Native Interface(JNI) technology is used to encapsulate self-developed and opensource biologic network comparison algorithm existing in the network, and issues them as Web Services. SVG and AJAX are used to implement interactive visualization. Functions of PSE-Bio such as task submission, task backing and result visualization can be implemented only with the browser. PSE-Bio is easy to use and extend.

Key words: Web Service, roblem Solving Environment(PSE), ioinformatics, visualization

摘要： 为了高效地整合互联网上各种分布式异构生物信息学资源，基于Web Service的生物信息学问题求解平台PSE-Bio使用统一的客户端生成器，便于加入多个以网络服务描述语言形式提供的生物信息学服务。PSE-Bio通过Java本地接口技术包装其自有的以及网络中开源的生物网络比对算法，并将其发布为Web服务，通过PSE-Agent实现对资源的有效管理，用SVG与AJAX实现交互式可视化。PSE-Bio基于浏览器完成任务提交、任务返回和结果可视化等任务，具有良好的易用性和可扩展性。

关键词: Web服务, 题求解平台, 物信息学, 视化

CLC Number: 

• TP311.12