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计算机工程 ›› 2026, Vol. 52 ›› Issue (11): 423-434. doi: 10.19678/j.issn.1000-3428.0252152

• 交叉融合与工程应用 • 上一篇    

相似实例引导下融合异质图的医学影像报告生成

李俊亮1, 马俊朋2, 刘梦萱3, 刘玉雪1, 张俊三1   

  1. 1. 中国石油大学(华东)青岛软件学院、计算机科学与技术学院, 山东 青岛 266580;
    2. 山东浪潮智慧医疗科技有限公司, 山东 济南 250000;
    3. 济南市第三人民医院重症医学科, 山东 济南 250132
  • 收稿日期:2025-02-21 修回日期:2025-04-29 发布日期:2025-06-03
  • 作者简介:李俊亮(CCF学生会员),男,硕士研究生,主研方向为医学图像理解、自然语言处理;马俊朋,高级工程师;刘梦萱,主治医师;刘玉雪,硕士研究生;张俊三(通信作者),教授、博士,E-mail:zhangjunsan@upc.edu.cn。
  • 基金资助:
    山东省自然科学基金(ZR2020MF006,ZR2022LZH015)。

Similar Instance Guidance Combining Heterogeneous Graph for Medical Image Report Generation

LI Junliang1, MA Junpeng2, LIU Mengxuan3, LIU Yuxue1, ZHANG Junsan1   

  1. 1. Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, Shandong, China;
    2. Shandong Inspur Intelligent Medical Technology Co., Ltd., Jinan 250000, Shandong, China;
    3. Intensive Care Unit, The Third Hospital of Jinan, Jinan 250132, Shandong, China
  • Received:2025-02-21 Revised:2025-04-29 Published:2025-06-03

摘要: 医学影像报告自动生成任务存在影像对比度低、异常区域较小的问题,仅依靠影像信息难以精准刻画异常特征,因此如何引入外部知识来增强视觉表征成为解决问题的关键。此外,异常特征的共现关系复杂,依赖单一样本难以捕捉,如何利用相似实例建模共现模式至关重要。针对上述挑战,提出一种融合异质图的相似实例引导(SIG)方法,用于生成医学影像报告,包括结合异质图的图像特征记忆模块和相似实例特征融合(SIFF)模块。结合异质图的图像特征记忆模块提取报告实体关系,构建与报告对应的异质图为桥梁,引导模型关注图像异常区域,增强异常视觉特征;SIFF模块检索相似实例,融合相似实例的异常视觉特征,在增强异常区域特征表达的同时,获取更全面的异常信息。在 IU X-Ray 和 MIMIC-CXR 这两个医学影像数据集上验证所提方法的有效性,实验结果表明,所提方法在 BLEU 系列评分指标上表现优秀,在IU X-Ray数据集上BLEU-1~BLEU-4分别为 0.539、0.353、0.265、0.193。同时,该方法在 METEOR 和 ROUGE-L 指标上的表现同样卓越。所提方法在自然语言生成指标和生成报告的准确性、完整性方面优于现有主流方法。

关键词: 医学影像报告生成, 相似实例引导, 异质图, 特征融合, 图像-文本生成

Abstract: Medical report generation from images is challenging owing to the low image contrast and small size of abnormal regions, making it difficult to accurately capture abnormal features using visual information alone. Therefore, the introduction of external knowledge to enhance visual representations is a key issue. Additionally, the co-occurrence patterns of abnormal features are complex and cannot be effectively captured from a single instance, making it crucial to leverage similar cases to model such patterns. To address these challenges, a Similar Instance Guidance (SIG) approach that fuses heterogeneous graphs for medical image report generation is presented. This approach consists of two main components: an image feature memory module incorporating heterogeneous graphs and a Similar Instance Feature Fusion (SIFF) module. The image feature memory module incorporating heterogeneous graphs extracts entity relationships from reports and constructs a corresponding heterogeneous graph as a bridge, guiding the model's attention to the abnormal regions of the image, thus enhancing abnormal visual features. SIFF retrieves similar instances and integrates their abnormal visual features, thereby augmenting the representation of abnormal regions, while acquiring a more comprehensive understanding of the abnormal information. To verify the effectiveness of the proposed method, experiments are conducted on both IU X-Ray and MIMIC-CXR datasets. The results indicate that the proposed method outperforms baseline methods on BLEU-based metrics, yielding BLEU-1-BLEU-4 values of 0.539, 0.353, 0.265, and 0.193, respectively, on the IU X-Ray dataset. Additionally, it excels in the METEOR and ROUGE-L metrics, indicating that the proposed method outperforms existing methods in terms of natural language generation metrics as well as the accuracy and completeness of the generated reports.

Key words: Medical image Report Generation (MRG), Similar Instance Guidance (SIG), heterogeneous graph, feature fusion, image—text generation

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